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Racial differences in salivary sIgA concentrations in postmenopausal women.

Identifieur interne : 000440 ( Main/Exploration ); précédent : 000439; suivant : 000441

Racial differences in salivary sIgA concentrations in postmenopausal women.

Auteurs : Roger B. Johnson [États-Unis]

Source :

RBID : pubmed:15984177

Descripteurs français

English descriptors

Abstract

The purpose of this study was to compare sIgA salivary concentrations between Caucasian and African-American postmenopausal women. The age, height, weight and history of hormone replacement therapy were recorded and the BMI was calculated for each individual. Whole, stimulated saliva was assayed for sIgA and total protein. Logistic regression analysis evaluated the relationships between the outcome variables. Total salivary sIgA and adjusted sIgA (adjusted for protein) concentrations were significantly higher in the African-American women (p<0.01). There were significant statistical correlations between sIgA concentrations and race (p<0.01). Our data suggest that racial differences in salivary sIgA concentrations in elderly women could be an important variable for planning future studies utilizing salivary samples as biological markers.

DOI: 10.1111/j.1754-4505.2005.tb01425.x
PubMed: 15984177


Affiliations:


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<term>Body Height (MeSH)</term>
<term>Body Mass Index (MeSH)</term>
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<term>Adulte d'âge moyen (MeSH)</term>
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<term>Débit sécrétoire (MeSH)</term>
<term>Facteurs âges (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Hormonothérapie substitutive (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Immunoglobuline A sécrétoire (analyse)</term>
<term>Indice de masse corporelle (MeSH)</term>
<term>Poids (MeSH)</term>
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<term>Post-ménopause (immunologie)</term>
<term>Protéines et peptides salivaires (analyse)</term>
<term>Salive (immunologie)</term>
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<term>Facteurs âges</term>
<term>Femelle</term>
<term>Hormonothérapie substitutive</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
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<div type="abstract" xml:lang="en">The purpose of this study was to compare sIgA salivary concentrations between Caucasian and African-American postmenopausal women. The age, height, weight and history of hormone replacement therapy were recorded and the BMI was calculated for each individual. Whole, stimulated saliva was assayed for sIgA and total protein. Logistic regression analysis evaluated the relationships between the outcome variables. Total salivary sIgA and adjusted sIgA (adjusted for protein) concentrations were significantly higher in the African-American women (p<0.01). There were significant statistical correlations between sIgA concentrations and race (p<0.01). Our data suggest that racial differences in salivary sIgA concentrations in elderly women could be an important variable for planning future studies utilizing salivary samples as biological markers.</div>
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